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KVSR SESHU KUMAR
Technical Director
M/s. Purview Lifesciences Pvt. Ltd.
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F.No: 403, KSR Vinayaka Residency, Kousalya Nagar,
Behind Volvo Service Station, Bachupally,
Hyderabad - 500 090. Telangana. India.
About
Senior Management Professional offering nearly 27 years of rich experience in API’s manufacturing industries. Proven abilities to enhance the production through process optimizations, optimizing resource & capacity utilization, escalate productivity & operational efficiencies. Skilled in production planning, cost control, solvent recovery, trouble shooting, technology transfer, piloting and scale up of new products.
A keen planner with skills in conceptualizing and effecting process initiatives to enhance plant efficiency and productivity. Conversant with techniques like Total Productive Maintenance and Overall Equipment Effectiveness. Well versed with TQM & Safety Norms. Proven abilities in managing technically advanced, cost efficient systems and processes. Keen understanding of formalities and implementation of quality systems and complying with the norms of regulatory authorities. An enterprising leader with abilities in leading multi-skilled motivated teams. Resourceful in interfacing with the Pollution Control Board, Govt. Depts. for various Certifications, Approvals, Audits, Clearances, etc. Ensuring compliance to quality standards and maintaining all related documents.
Wide exposure in development and scale up of various Drugs and intermediates.
Experience
Areas of Expertise
Selection of a product based on market and suitability of plant. Process development and scale up.
- Plant Operations
- Cost Optimization
- Quality Assurance & Control
- Equipment Utilization
- New Product Launching
- Dispatch Planning
- Production Management & Planning
- Resource Deployment
- Yield Improvement
- Trouble Shooting
- EHS Operations
- Materials Management
- Process Enhancement
- Technology Upgradation/ Transfer
- Liaison and Coordination
- Marketing
- Procurement / Vendor Management
- Documentation
Academia
Major Achievements
- Successfully developed the process of SUCRALOSE ( Zero calories sugar) from sugar. We have developed this process in R&D and commercialized the same up to 200 kg level.
- The commonly used Triphenyl phosphine synthesis from Triphenyl phosphine oxide, which is a byproduct of many cephalosporin drugs.
- We have started the innovative production of TRIPHENYL PHOSPHINE (TPP) in 2011. Recently, Patent issued for the same.
- The production of TPP is an innovative route, it has been developed in our R&D and successfully commercialised. In general, TPP was produced from PCl3, Sodium metal and Mono chloro benzene.
- But we synthesised this product from Triphenylphosphine oxide reaction with Triphosgene and Aluminium. The Triphenyl phosphine oxide is a waste product while making the CEFIXIME and other cephalosporins.
- Presently, we are producing TPP about 100MT per month.
- Since 2016, simultaneously we are producing the Triphenyl phosphine with PCl3 and MCB by Grignard reaction including the 93 % recovery of THF solvent.
- Dimethyl acetone dicarboxylate
- L-Glutamic acid-5- benzyl ester
- Diethyl-D(-) tartrate
- Di-P- toluyl- D- Tartaric acid
- L-Pyroglutamic acid
- N-Boc-L-PyroGlutamic acid ethyl ester
- 4- Chloropyridine-3- sulphonamide
- 2-OXO piperazine
- N,N-Dimethyl Thio Urea
- Sulfurtrioxide-pyridine complex
Publications
Rapid and Selective Oxidation Of Alcohols Using Fly Ash Mediated KMnO4 (KMnO4-FY) Under Solvent Free Conditions
International Journal of New Technologies in Science and Engineering Vol. 2, Issue 6,Dec 2015.
Facile synthesis and anti-microbial properties of 2-(Substituted benzyl sulphanyl)-1HBenzimidazoles.
J. Heterocyclic Chemistry, 42, 1405, 2005.
Facile synthesis of 2-(Substituted benzyl sulphanyl)-1H- Benzothiazoles and its anti-microbial activity screening.
J. Heterocyclic Chemistry, 42, 153, 2005.
Simple and convenient synthesis of 2-(Substituted benzyl sulphanyl)-4,5- Dihydrothiazoles and their anti-microbial activity studies.
J. Heterocyclic Chemistry, 42, 1191, 2005.
Patent
PROCESS FOR PREPARING TRIPHENYLPHOSPHINE.
Patent No: 33655
Application No: 201741023474
Management
- Monitoring the daily statements of Finance, funds status, debtors and creditors statements and monthly balance sheet.
- Overseeing production related tasks including planning, procurement, & troubleshooting for manufacturing API bulk drugs thereby achieving the planned quantity and periodic schedules.
- Developing new process concepts for production optimization, yield improvement.
- Controlling all departments to resolves the issues.
- Review of SOP’s, manuals & work instructions for production operations facilitating decision making.
- Monitoring the Purchase, R&D, QA, QC and marketing departments to ensure timely delivery of products to customers.
- Troubleshooting related to production activities such as yields fluctuations, quality problems etc.
- Monitoring processes & identifying deviations towards ensuring reproducibility and consistency.
- Analysing various processes/applications and recommending modifications & equipment selections to enhance operational efficiency.
- Devising cost saving measures & modifications to achieve substantial reduction in terms of man days, production cost, raw material & energy consumption.
- Leading the implementation of qualitative assurance across raw materials, work in progress and finished goods across various functional departments.
- Conducting regular internal audits, root cause analysis, troubleshooting and reviews to ensure adherence to highest standards.
- Training and guiding teams towards identifying factors critical to quality, reducing process variation, improving capabilities & increasing consistency and stability.
- Leading, mentoring & monitoring the performance of the team to ensure efficiency in process operations & meeting of individual & group targets.
- Ensuring that teams adhere to all the quality tool & procedures.
